ASL Quantitative analysis

• Drag the M0 image into the window to activate the quantitative analysis.
• Coregister the two series if this is not done already.
• If you don't want to do quantitative analysis, you can ignore the M0 image.
• You can estimate the blood M0 either using a fixed value, or from a pixel-wise analysis.
• If you use a fixed value, you can use autodetect to set the CSF threshold, or change the slider. This will update the mean signal of CSF. Use 1 for no correction. Note that the red indication of the segmented area used for CSF reference signal will only be visible when the <Blood M0 estimation> option is set to <Fixed-value Mo>. Note that the mean signal of CSF is set to a higher value that the cutoff-value for the CSF auto-detect since this is the lower cutoff value.

Under the Options tab, you can apply additional corrections to the M0 map. These are only available if Blood M0 estimation is done using a pixel-wise analysis.

Additionally, the output can be normalized to CBF.